Posaconazole

In the US, Posaconazole (posaconazole systemic) is a member of the drug class azole antifungals and is used to treat Aspergillosis - Invasive, Candida Infections - Systemic and Oral Thrush.

US matches:

• Posaconazole Suspension


• Posaconazole

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J02AC04

CAS registry number (Chemical Abstracts Service)

0171228-49-2

Chemical Formula

C37-H42-F2-N8-O4

Molecular Weight

700

Therapeutic Category

Antifungal agent

Chemical Names

(3R-cis)-4-[4-[4-[4-[5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3-ylmethoxy]-phenyl]piperazin-1-yl]phenyl]-2-[1(S)-ethyl-2(S)-hydroxypropyl]-3,4-dihydro-2H-1,2,4 -triazol-3-one

1-[(1S,2S)Ethyl-2-hydroxypropyl]-2,3-dihydro-4-{4-[4-(4-{2-[(2S,4R)-(1,2,4-triazol-1-ylmethyl)-2-(2,4-difluorphenyl)oxolan-4-ylmethyl]phenyl}piperazin-1-yl)phenyl]}-1,2,4-triazol-3-on (IUPAC)

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-(4-[1-(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol

3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-(1-ethyl-2-hydroxypropyl)-2,4-dihydro-, [3R-[3α(1S*,2S*),5α]]- (USAN)

4-[4-(4-{4-[(3R,5R)-5-]2,4-Difluorophenyl}tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furylmethoxy]phenyl}piperazin-1-yl)phenyl]-2-[(1S,2S)-1-ethyl-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one (BAN)

4-[p-[4-[p-[[(3R,5R)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl]methoxy]phenyl]-1-piperazinyl]phenyl]-1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-delta²-1,2,4-triazolin-5-one (WHO)

Foreign Names

• Posaconazolum (Latin)
• Posaconazol (German)
• Posaconazole (French)
• Posaconazol (Spanish)

Generic Names

• Posaconazole (OS: USAN, BAN)
• SCH 56592 (IS: ScheringPlough)

Brand Names

• Noxafil
  Essex, Germany; Essex Chemie, Switzerland; Sanofi-Aventis, Croatia (Hrvatska); Schering, Belgium; Schering, Czech Republic; Schering, United States; Schering-Plough, Australia; Schering-Plough, Spain; Schering-Plough, Finland; Schering-Plough, France; Schering-Plough, United Kingdom; Schering-Plough, Hungary; Schering-Plough, Ireland; Schering-Plough, Italy; Schering-Plough, Netherlands; Schering-Plough, Norway; Schering-Plough, Sweden; Schering-Plough, Slovenia; Schering-Plough, Slovakia; SP Europe, Austria; SP Europe, Denmark



• Posanol
  Schering-Plough, Canada

International Drug Name Search

Glossary

BAN	British Approved Name
IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.